Does Omega XL Really Work?
Updated 2025

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We put dozens of pain relief and joint pain supplements to the test 
with our rigorous system to find the "Best of the Best" 

If you've ever been sidelined by pain, you know how it can completely take over your life.  Pain relief and anti-inflammatory supplements are a great way to help manage your pain, especially if you're looking for something that's not as strong as prescription medications.

There's no doubt that prescription painkillers and other medications can be incredibly helpful in managing pain, but they're also highly addictive and come with serious side effects. They can also be dangerous if taken incorrectly or without proper supervision from a doctor.  Over-the-counter pain medications are not ideal either, the risk of taking the wrong dose and damaging vital organs is real and fairly common.  The question is - what do you take if you are in pain and do not want the risks of drugs or OTC medications? 

Pain relief and anti-inflammatory supplements are a great way to help manage your pain, especially if you're looking for something that's not as risky as prescription medications.  It's no wonder that so many people turn to these supplements in search of relief. But with the market for these products booming—and new ones popping up all the time—it can be hard to figure out what's best for your situation.

That's where we come in. We've reviewed dozens of pain relief supplements, from big-name brands to high-dollar options, and tested them on ourselves as well as our friends and family members who suffer from pain. We surveyed thousands of people and customer reviews as well as analyzed the leading research on all-natural pain relief and anti-Inflammatory supplements.  Through this rigorous process, we've found some real gems—and we're here to share them with you now.

Our Research-Backed 10-Point System

When choosing a pain relief supplement, just going with any off-the-shelf brand doesn't cut it.

Here at Smart Review Today, we use a proven 10-point ranking system to test and compare all of our products. To make an educated decision, you need to know how our system works. 

We analyze the following:
  • All-natural ingredients are sourced ethically.
  • ​Ensuring the products are formulated properly for maximum effectiveness.
  • The presence of harmful material/ingredients.
  • ​The science, research, and development behind the product.
  • The manufacturer upholds high quality assurance protocols.
  • ​High-quality, regulated manufacturing facilities and processes.
  • ​Discussions with customers and users of the product.
  • ​Customer reviews – removing fake/paid reviews so only real opinions count.
  • ​Price. Is it worth the money?
  • ​Return policy and money-back guarantee.

Pros:

  • 100% Drug-Free, All-Natural Formula
  • ​Blend of Premium Ingredients Optimized to                Relieve Pain and Increase Mobility
  • No auto-ship, recurring payments, or                             subscriptions
  • ​Contains Turmeric Root Extract, Ginger,                         Boswellia Serrata & Type II Collagen
  • ​Made in the USA at GMP Certified Facility 
  • ​Easy to Take Dosage
  • ​US-Based Customer Service Team 
  • Industry Leading 90-Day Money Back                            Guarantee with No Catches

Cons:

  • Only Available Online
  • Sells Out Often

The Bottom Line:

FlexGuard by Paragon Wellness is our Number 1 Pick for a variety of reasons.  FlexGuard is the only supplement that "checked all of the boxes" in our review list.

FlexGuard’s formula is really what makes this product stand out. Not just because the ingredients are all-natural, but because of the potency and quality of the ingredients. The proper mix of Turmeric, ginger, collagen, and boswellia extract works together to relieve pain and discomfort naturally.  The best part of it is that you will start to see results in the first week.  Not only does it work fast, but FlexGuard continues to become more effective over the next several weeks so you can start living your life with less pain.  All of this with two easy doses per day.  Simply put, FlexGuard delivers because it uses scientifically backed ingredients. 

FlexGuard is also a great value.  There are no auto-shipments or subscriptions.  Just buy what you want, when you want.  Paragon Wellness often runs specials for our readers to get the best price on this high-quality product.  The best part is that if you are still not sure, Paragon Wellness offers a 90-day 100% satisfaction, money-back guarantee on FlexGuard. This guarantee gives added peace of mind.  

At first we were skeptical, but after putting FlexGuard to the test, we are convinced.  We have no doubt at all about FlexGuard's quality and effectiveness. Backed by scientific research, top-notch ingredients, and the 90-day money-back guarantee on it, we are confident our #1 pick is the only natural pain relief supplement needed. 

2nd Place:  Instaflex

Pros:

  • ​Contains Natural Ingredients 
  • Nice Ads and Packaging
  • Good Customer Support

Cons:

  • Subscription with auto-shipments
  • Not All Ingredients Backed by Science
  • ​No Ingredients to Improve Joint Health
  • Poor Return Policy

The Bottom Line:

Instaflex is our second pick because it's a well-known brand that makes a quality product. However, they fell into the second spot for a few reasons.

First, although Instaflex has ingredients that could be effective, some included ingredients do not have strong scientific backing. This is perplexing because the suggested dose of Instaflex is three capsules per dose. This product contains turmeric, which is a good thing. However, it may not be absorbed as well by the body without black pepper extract. It also does not contain collagen, which is a key ingredient in our top-rated product on the list. Finally, this product ranks second because it  includes glucosamine, which has not been proven to support joint health. Instaflex is the perfect example of more not always being better. Our bodies need proper doses of high-quality, scientifically studied ingredients, not the "everything but the kitchen sink" approach.

Instaflex entices customers with a low up-front cost, but automatically enrolls them in an auto-ship program. If you're not careful, you'll be signed up for a subscription that automatically renews at $69.95 plus shipping and handling every month. Moreover, the return policy is only 30 days. The manufacturer will not accept a return of any shipment that is more than 30 days old. How are you supposed to know if it works with such a restrictive return policy?

If some of these issues were improved, we may consider giving this product a stronger recommendation.

3rd Place: Omega XL

Pros:

  • All Natural Ingredients
  • Money Back Guarantee
  • Popular Brand

Cons:

  • Expensive
  • Unclear about Potency of Ingredients
  • Mixed Customer Reviews.  

The Bottom Line:

Omega XL ranks #3 for several reasons. Overall it just doesn't stack up to the other two products we reviewed.

Although Omega XL's formula seems exotic and their advertising is very convincing, there are some deficiencies.  The main ingredient has some tangential evidence to support joint pain relief, but the formula is lacking in overall effectiveness.  The other products reviewed have much more well-rounded formulas and clinically studied ingredients that actually fight pain where it starts - inflammation. To combat this weak formula, the manufacturer offers bonus products.  However, if you do the math, theses bundles are not worth the money.  More importantly, why take multiple supplements, when one effectively formulated supplement will do the job?
   
This would be a solid option if it wasn't for these facts.  The formula doesn't justify the expense. If some of these items were improved, we may consider giving this product a stronger recommendation.

Pros:

  • 100% Drug-Free, All-Natural Formula
  • ​Blend of Premium Ingredients Optimized to                Relieve Pain and Increase Mobility
  • No auto-ship, recurring payments, or                             subscriptions
  • ​Contains Turmeric Root Extract, Ginger,                         Boswellia Serrata & Type II Collagen
  • ​Made in the USA at GMP Certified Facility 
  • ​Easy to Take Dosage
  • ​US-Based Customer Service Team 
  • Industry Leading 90-Day Money Back                            Guarantee with No Catches

Cons:

  • Only Available Online
  • Sells Out Often

The Bottom Line:

FlexGuard by Paragon Wellness is our Number 1 Pick for a variety of reasons.  FlexGuardGuard is the only supplement that "checked all of the boxes" in our review list.

FlexGuard’s formula is really what makes this product stand out. Not just because the ingredients are all-natural, but because of the potency and quality of the ingredients. The proper mix of Turmeric, ginger, collagen, and boswellia extract works together to relieve pain and discomfort naturally.  The best part of it is that you will start to see results in the first week.  Not only does it work fast, but FlexGuard continues to become more effective over the next several weeks so you can start living your life with less pain.  All of this with two easy doses per day.  Simply put, FlexGuard delivers because it uses scientifically backed ingredients. 

FlexGuard is also a great value.  There are no auto-shipments or subscriptions.  Just buy what you want, when you want.  Paragon Wellness often runs specials for our readers to get the best price on this high-quality product.  The best part is that if you are still not sure, Paragon Wellness offers a 90-day 100% satisfaction, money-back guarantee on FlexGuard. This guarantee gives added peace of mind.  

We have no doubt at all about FlexGuard's quality and efficacy. Backed by scientific research, top-notch ingredients, and the 90-day money-back guarantee on it, we are confident our #1 pick is the only natural pain relief supplement needed. 
*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information provided by this website or this company is not a substitute for a face-to-face consultation with your physician and should not be construed as individual medical advice. The testimonials on this website are individual cases and do not guarantee that you will get the same results. All content, including text, graphics, images and information, contained on or available through this web site is for general information purposes only.